Prevention of angina pectoris caused by coronary artery disease
Abdominal pain, arm, back or jaw pain, black tarry stool, blurred vision, chills, cold sweats, cough
Hypersensitivity to organic nitrates.PDE-5 inhibitors (eg, avanafil, sildenafil, tadalafil, or vardenafil); concomitant use can cause severe hypotension, syncope, or myocardial ischemia. Concomitant administration with guanylate stimulator riociguat (may cause hypotension)
Use caution in acute myocardial infarction, alcohol use, hyperthyroidism, increased intracranial pressure (eg, from head trauma or cerebral hemorrhage; potential contraindication), increased intraocular pressure, postural hypotension, volume depletion, Moderate hypotension, low systolic blood pressure (BP)